Ssa Antibody Levels

Both anti ssa and anti ssa are usually absent in secondary sjögren s syndrome.

Ssa antibody levels.

Anti ro ssa antibodies are found in 40 90 of patients with systematic lupus erythematosus sle. Anti ssa levels may be elevated in the following conditions. Ss a ro is an extractable nuclear antigen ena composed of protein antigens of 52 kd and 60 kd combined with cytoplasmic rna species. The antibodies can be detected years before symptoms of sle surface making them an effective diagnostic tool.

A positive ana test means that you have high levels of ana in your blood. In the book the lupus book. When anti ssa levels are elevated in sle it is often in antinuclear antibody ana negative lupus. Systemic lupus erythematous sle.

Lupus erythematosus le 40 60 of. Sjögren s antibody ss b is present only if sjögren s antibody ss a is also detected. Ss a ro antibodies occur in patients with several different connective tissue diseases including sjogren syndrome an autoimmune disease that involves primarily the salivary and lachrymal glands up to 90 of cases. Sjogren s antibodies ss a ss b sjögren s antibodies ss b is detected in approximately 15 of patients with sjögren s syndrome.

The ssa antibody is usually found with the ssb antibody which means there is typically an anti ssb blood test ordered with the anti ssa test. A guide for patients and their families author daniel wallace explains that ssa plays a role in systemic lupus and categorizes it as a cell surface component. In patients with sle high levels of anti ro ssa are correlated with elevated levels of ifn α. The presence of both antibodies ss a and ss b strengthen the diagnosis of sjögren s syndrome and conveys prognostic information.